The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2016
Filed:
Aug. 30, 2013
Applicant:
Advanced Accelerator Applications, Saint Genis Pouilly, FR;
Inventors:
Annarita Del Gatto, Torre del Greco, IT;
Laura Zaccaro, Naples, IT;
Carlo Pedone, Naples, IT;
Michele Saviano, Milan, IT;
Assignee:
ADVANCED ACCELERATOR APPLICATIONS, Saint Genis Pouilly, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/46 (2006.01); C07K 7/64 (2006.01); C07K 14/745 (2006.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); C07K 14/46 (2013.01); C07K 14/745 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention is related to new peptide antagonists of αβreceptor, designed on the basis of the crystal structure of integrin αβin complex with c(RGDf[NMe]V) and the NMR structure of echistatin. These peptides are potent and selective antagonists of the αβreceptor and can be used as novel anticancer drugs and/or new class of diagnostic non-invasive tracers as suitable tools for αβ-targeted therapy and imaging.