The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2016
Filed:
Nov. 21, 2013
Applicant:
Rqx Pharmaceuticals, Inc., La Jolla, CA (US);
Inventors:
Tucker Curran Roberts, San Diego, CA (US);
Peter Andrew Smith, La Jolla, CA (US);
Robert I. Higuchi, Solana Beach, CA (US);
David Campbell, San Diego, CA (US);
Prasuna Paraselli, San Diego, CA (US);
Assignee:
RQX PHARMACEUTICALS, INC., La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/07 (2006.01); C07K 5/10 (2006.01); C07K 7/06 (2006.01); C07K 5/02 (2006.01); C07K 5/083 (2006.01); C07K 5/087 (2006.01); C07K 5/11 (2006.01); A61K 38/55 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 38/07 (2013.01); A61K 38/55 (2013.01); C07K 5/0202 (2013.01); C07K 5/081 (2013.01); C07K 5/0812 (2013.01); C07K 5/1019 (2013.01);
Abstract
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.