The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2016

Filed:

Jan. 30, 2015
Applicant:

Nerviano Medical Sciences S.r.l., Nerviano, IT;

Inventors:

Marina Caldarelli, Milan, IT;

Mauro Angiolini, Gavirate, IT;

Italo Beria, Nerviano, IT;

Maria Gabriella Brasca, Nerviano, IT;

Francesco Casuscelli, Dairago, IT;

Roberto D'Alessio, Cinisello Balsamo, IT;

Andrea Lombardi Borgia, Paullo, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61K 45/06 (2006.01); C07D 487/04 (2006.01); A61K 31/519 (2006.01); C07C 67/00 (2006.01); C07D 207/34 (2006.01); C07D 209/42 (2006.01); C07D 401/04 (2006.01); C12N 9/99 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07C 67/00 (2013.01); C07D 207/34 (2013.01); C07D 209/42 (2013.01); C07D 401/04 (2013.01); C12N 9/99 (2013.01);
Abstract

The present invention relates to tricyclic pyrrolo derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.


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