The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2016
Filed:
Apr. 02, 2013
Entasis Therapeutics Limited, London, GB;
Helen McGuire, Waltham, MA (US);
Shanta Bist, Waltham, MA (US);
Neil Bifulco, Waltham, MA (US);
Liang Zhao, Waltham, MA (US);
Ye Wu, Waltham, MA (US);
Hoan Huynh, Waltham, MA (US);
Hui Xiong, Waltham, MA (US);
Janelle Comita-Prevoir, Waltham, MA (US);
Daemian Dussault, Waltham, MA (US);
Bolin Geng, Waltham, MA (US);
Brendan Chen, Waltham, MA (US);
Thomas Durand-Reville, Waltham, MA (US);
Satenig Guler, Waltham, MA (US);
Entasis Therapeutics Limited, London, GB;
Abstract
The present invention is directed to compounds which are beta-lacatamase inhibitors. The compounds and their pharmaceutically acceptable salts, are useful in combination with beta-lactam antibiotics, or alone, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to formula (Ia): or a pharmaceutically acceptable salt thereof, wherein the values of R, R, Rand Rare described herein.