The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2016

Filed:

Mar. 12, 2013
Applicant:

Laboratorios Lesvi S.l., Barcelona, ES;

Inventors:

Jordi Benet-Buchholz, Tarragona, ES;

Jordi Cerón Bertran, Tarragona, ES;

Glòria Freixas Pascual, Tarragona, ES;

Pere Dalmases Barjoan, Barcelona, ES;

Isabel Navarro Muñoz, Barcelona, ES;

Assignee:

LABORATORIOS LESVI S.L., Barcelona, ES;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 231/24 (2006.01); C07C 231/16 (2006.01); C07C 233/43 (2006.01);
U.S. Cl.
CPC ...
C07C 233/43 (2013.01); C07C 231/16 (2013.01); C07C 231/24 (2013.01); C07B 2200/13 (2013.01);
Abstract

New polymorphic form of a long-acting beta-2 adrenoceptor agonist A new polymorphic form of arformoterol tartrate, designated as form D, is provided and which is characterized by at least one of the following: (i) a powder X-ray diffraction pattern having peaks at approximately 6.8, 13.3, 13.6, 3.8, 14.1, 18.2, 18.7, 20.0±0.2 degrees two theta; or (ii) a DSC thermogram showing an endothermic peak with an onset at approximately 19-120° C., and a maximum at approximately 129-131° C., followed by an exothermic peak with a maximum at approximately 137-138° C.; wherein the DSC thermogram of form D has a further endothermic peak with an onset at approximately 168-170° C.1 Processes for preparing the new polymorphic form, uses thereof and intermediates for the preparation thereof, are also provided.


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