The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2016
Filed:
Apr. 17, 2013
Applicant:
Cerion Enterprises, Llc, Rochester, NY (US);
Inventors:
Wendi Ann Costanzo, Webster, NY (US);
Kenneth Joseph Reed, Brighton, NY (US);
Bradford Michael Stadler, Brighton, NY (US);
Assignee:
CERION LLC, Rochester, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); C12N 15/00 (2006.01); A61K 31/00 (2006.01); A61K 47/18 (2006.01); A61K 33/24 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61K 9/51 (2006.01); B22F 9/24 (2006.01); B22F 1/00 (2006.01); A61K 47/48 (2006.01); C12N 15/87 (2006.01); B82Y 30/00 (2011.01); C01F 17/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/183 (2013.01); A61K 9/5115 (2013.01); A61K 9/5123 (2013.01); A61K 9/5192 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 33/24 (2013.01); A61K 47/48861 (2013.01); B22F 1/0018 (2013.01); B22F 1/0022 (2013.01); B22F 9/24 (2013.01); B82Y 30/00 (2013.01); C01F 17/0043 (2013.01); C12N 15/87 (2013.01); C01P 2002/60 (2013.01); C01P 2002/70 (2013.01); C01P 2002/72 (2013.01); C01P 2004/04 (2013.01); C01P 2004/64 (2013.01); C01P 2006/90 (2013.01);
Abstract
A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, an α-amino acid, an oxidant and water is provided along with temperature conditions to effectively form nanoparticles. These biocompatible nanoparticles may be further conjugated to biologically active agents, such as plasmid DNA, siRNA or proteins, such that a cell transfection agent is formed.