The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2016
Filed:
Nov. 23, 2011
Applicants:
Richard J. Bucala, Cos Cob, CT (US);
Lawrence H. Young, Woodbridge, CT (US);
Inventors:
Richard J. Bucala, Cos Cob, CT (US);
Lawrence H. Young, Woodbridge, CT (US);
Assignee:
Yale University, New Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 39/395 (2006.01); C07K 16/24 (2006.01); C12Q 1/68 (2006.01); A61K 31/713 (2006.01); A61K 38/02 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/713 (2013.01); A61K 38/02 (2013.01); C07K 16/24 (2013.01); C12Q 1/6883 (2013.01); G01N 33/6893 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present invention relates to the discovery that reduced levels of D-dopachrome tautomerase (D-DT) (also known as MIF-2) are associated with ischemia-reperfusion injury. Thus, the present invention relates to methods of administering D-DT and recombinant D-DT for the treatment of ischemia-reperfusion injury.