The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2016

Filed:

Oct. 08, 2010
Applicants:

Luis Garcia, Bailly, FR;

Stéphanie Lorain, Vincennes, FR;

Inventors:

Luis Garcia, Bailly, FR;

Stéphanie Lorain, Vincennes, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 5/00 (2006.01); C07K 14/47 (2006.01); A61K 48/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4708 (2013.01); A61K 48/005 (2013.01); C12N 15/85 (2013.01); C12N 2840/445 (2013.01); C12N 2840/85 (2013.01);
Abstract

The present invention provided methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated simple or double trans-splicing. The compositions of the invention include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and to mediate a simple or double trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (Chimeric RNA).


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