The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2016
Filed:
Apr. 30, 2012
Applicants:
Scott C. Blanchard, New York, NY (US);
Ronald Micura, Innsbruck, AT;
Andrea Haller, Innsbruck, AT;
Inventors:
Assignees:
CORNELL UNIVERSITY, Ithaca, NY (US);
LEOPOLD-FRANZENS UNIVERSITAT INNSBRUCK, Innsbruck, AT;
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07H 21/02 (2006.01); C12N 15/115 (2010.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); C12N 15/115 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3519 (2013.01); C12N 2320/50 (2013.01); G01N 2021/6432 (2013.01); Y10T 436/143333 (2015.01);
Abstract
The present invention is provides isolated riboswitches with FRET pairs for distinguishing changes in regulatory interactions controlled by the expression platform domain found in riboswitches. The invention further provides methods of using those riboswitches to detect structural changes in the expression platform domain and to identify potential antibiotics.