The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2016
Filed:
Dec. 05, 2014
Applicant:
Eisai R&d Management Co., Ltd., Tokyo, JP;
Inventors:
Huiming Zhang, Andover, MA (US);
Bryan M. Lewis, North Brunswick, NJ (US);
Assignee:
Eisai R&D Management Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 321/00 (2006.01); C07D 493/22 (2006.01);
U.S. Cl.
CPC ...
C07D 493/22 (2013.01);
Abstract
In general, the present invention features improved methods useful for the synthesis of analogs of halichondrin B, such as eribulin and pharmaceutically acceptable salts thereof (e.g., eribulin mesylate).