The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2016
Filed:
Dec. 18, 2014
Shanxi Zhendong Pilot Biological Science and Technology Co., Ltd., Jinzhong, Shanxi, CN;
Weidong Zhang, Shanghai, CN;
Lei Shan, Shanghai, CN;
Huizi Jin, Shanghai, CN;
Juan Su, Shanghai, CN;
Huiliang Li, Shanghai, CN;
Yunheng Shen, Shanghai, CN;
Xike Xu, Shanghai, CN;
Runhui Liu, Shanghai, CN;
Abstract
Preparation and application of line leafflower lactone A for treating myocarditis having a structure of The compound shows positive therapeutic activity against Coxsackie virus and significant dose dependent correlation. The line leafflower lactone A prevents disease in mouse models of experimental autoimmune myocarditis and onset of the process by intraperitoneal injection of a dose of 20 mg/kg/d. When increased to 100 mg/kg/d, the line leafflower lactone A shows positive therapeutic effect on EAM. Line leafflower lactone A is used as the sole active ingredient and combined with a conventional pharmaceutical carrier in a drug for treating myocarditis, and the pharmaceutical composition may be in the form of tablets, dispersible tablets, mouth collapse tablets, retard tablets, capsule, soft capsule, dropping pill, granules, injection, powder injection, or aerosol.