The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2016
Filed:
Jun. 06, 2014
Applicant:
Xenoport, Inc., Santa Clara, CA (US);
Inventors:
Stephen P. Raillard, Mountain View, CA (US);
Randall A. Scheuerman, Santa Clara, CA (US);
Suresh K. Manthati, Sunnyvale, CA (US);
Assignee:
XenoPort, Inc., Santa Clara, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/185 (2006.01); C07C 67/08 (2006.01); C07C 67/333 (2006.01); C07C 67/14 (2006.01); C07C 231/12 (2006.01);
U.S. Cl.
CPC ...
C07C 67/14 (2013.01); C07C 67/08 (2013.01); C07C 67/333 (2013.01); C07C 231/12 (2013.01); C07D 295/185 (2013.01);
Abstract
Methods of making monomethyl fumarate, which can then also be used in methods of making prodrugs of monomethyl fumarate, are disclosed. Monomethyl fumarate and prodrugs of monomethyl fumarate are useful for treating neurodegenerative, inflammatory, and autoimmune diseases including multiple sclerosis, psoriasis, irritable bowel disorder, ulcerative colitis, arthritis, chronic obstructive pulmonary disease, asthma, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis.