The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2016

Filed:

Sep. 07, 2012
Applicants:

Jean Herman, Heverlee, BE;

Thierry Louat, Heverlee, BE;

Qiuya Huang, Leuven, BE;

Bart Vanderhoydonck, Diest, BE;

Mark Waer, Heverlee, BE;

Piet Herdewijn, Rotselaar, BE;

Inventors:

Jean Herman, Heverlee, BE;

Thierry Louat, Heverlee, BE;

Qiuya Huang, Leuven, BE;

Bart Vanderhoydonck, Diest, BE;

Mark Waer, Heverlee, BE;

Piet Herdewijn, Rotselaar, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); G01N 33/564 (2006.01); A61K 31/5377 (2006.01); A61K 31/519 (2006.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/426 (2013.01); A61K 31/519 (2013.01); G01N 33/564 (2013.01); G01N 33/573 (2013.01); G01N 2333/91215 (2013.01); G01N 2500/02 (2013.01);
Abstract

Compounds that bind to phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) and inhibit the binding of PI4KIIIβ to its substrate and/or inhibit PI4KIIIβ activity may be used in the treatment and/or prevention of an autoimmune or inflammatory disorder, or organ or cell transplant rejection. A new assay for identifying compounds for use in treating and/or preventing those pathological conditions, which comprises measuring the inhibition of PI4KIIIβ activity, is also disclosed.


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