The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2016

Filed:

Jul. 30, 2014
Applicant:

Intelgenx Corp., St.-Laurent, Quebec, CA;

Inventors:

Horst G. Zerbe, Quebec, CA;

Angela Angusti, Montreal, CA;

Nadine Paiement, St.-Laurent, CA;

Assignee:

IntelGenx Corp., St.-Laurent, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4196 (2006.01); A61K 47/02 (2006.01); A61K 47/32 (2006.01); A61K 47/38 (2006.01); A61K 9/00 (2006.01); A61K 31/422 (2006.01); A61K 31/473 (2006.01); A61K 31/5513 (2006.01); A61K 31/5517 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4196 (2013.01); A61K 9/006 (2013.01); A61K 31/422 (2013.01); A61K 31/473 (2013.01); A61K 31/5513 (2013.01); A61K 31/5517 (2013.01); A61K 47/02 (2013.01); A61K 47/32 (2013.01); A61K 47/38 (2013.01);
Abstract

An instantly wettable and rapidly disintegrating oral film dosage form without a surfactant and without a polyalcohol was achieved by combining at least one water soluble polymer that is not a copolymer of vinylpyrrolidone, at least one active agent, a copolymer of vinylpyrrolidone and titanium dioxide. In certain embodiments, the film comprises hydroxypropyl cellulose or a combination of hydroxypropyl cellulose and a polymer or copolymer of vinylpyrrolidone or a substituted vinylpyrrolidone as the water soluble polymer(s). A plasticizer, and optional additives selected from synthetic sweeteners, natural sweeteners, flavorants, antioxidants, colorants, and opacifiers, can be added to the disclosed film oral dosage forms.


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