The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2016

Filed:

Oct. 14, 2011
Applicants:

Masanori Fukushima, Kyoto, JP;

Hiroaki Matsubara, Kyoto, JP;

Satoaki Matoba, Kyoto, JP;

Shigeki Hijikata, Tokyo, JP;

Yu Aso, Tokyo, JP;

Tsutomu Sato, Tokyo, JP;

Inventors:

Masanori Fukushima, Kyoto, JP;

Hiroaki Matsubara, Kyoto, JP;

Satoaki Matoba, Kyoto, JP;

Shigeki Hijikata, Tokyo, JP;

Yu Aso, Tokyo, JP;

Tsutomu Sato, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 9/00 (2006.01); A61K 31/7004 (2006.01); A61K 31/7008 (2006.01); A61K 45/06 (2006.01); A61K 38/39 (2006.01); A61K 9/51 (2006.01); A61K 47/26 (2006.01); A61K 47/42 (2006.01); A61K 38/27 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0002 (2013.01); A61K 9/0024 (2013.01); A61K 9/5123 (2013.01); A61K 31/7004 (2013.01); A61K 31/7008 (2013.01); A61K 38/1825 (2013.01); A61K 38/39 (2013.01); A61K 45/06 (2013.01); A61K 47/26 (2013.01); A61K 47/42 (2013.01); A61K 38/1808 (2013.01); A61K 38/1816 (2013.01); A61K 38/1858 (2013.01); A61K 38/27 (2013.01);
Abstract

Provided is a pharmaceutical composition, including a drug and a collagen, in which the composition is satisfactory in handleability and has sustained-release property. The sustained-release pharmaceutical composition includes: a drug; a collagen; and at least one kind of sugar selected from monosaccharides, disaccharides, trisaccharides, and tetrasaccharides. The inventors of the present invention have found that the in vivo administration of a collagen solution containing a sugar results in the gelation of a collagen. Based on this finding, the inventors have found that a composition containing a drug, a collagen, and a sugar can control the release rate of the drug, and such composition can be used as a sustained-release pharmaceutical composition.


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