The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2016
Filed:
Mar. 15, 2013
Caliper Life Sciences, Inc., Hopkinton, MA (US);
Joshua I. Molho, Oakland, CA (US);
Daniel G. Stearns, Los Altos Hills, CA (US);
I-Jane Chen, Alameda, CA (US);
Danh Tran, Hayward, CA (US);
Bradley W. Rice, Danville, CA (US);
Tobias Daniel Wheeler, Alameda, CA (US);
Alexander V. Dukhovny, San Francisco, CA (US);
CALIPER LIFE SCIENCES, INC., Hopkinton, MA (US);
Abstract
The invention provides devices, systems, and methods for extracting target objects from a sample. In the method, a stream of sample containing a plurality of target and non-target objects is directed by first and second streams of buffer through a sample inlet channel into a fluid junction and through the fluid junction into a sample waste channel. In response to detecting a target object within the stream of sample, an actuator is energized to close a normally open valve, resulting in a transient burst of cross-flow into the fluid junction that briefly diverts the flow of sample within the fluid junction and results in an aliquot of sample being directed into an aliquot delivery channel. The combination of the valve and the actuator acts as a self-limiting pulse generator.