The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2016
Filed:
Feb. 18, 2013
Applicant:
Hoffmann-la Roche Inc., Nutley, NJ (US);
Inventors:
Klaus Christensen, Oberwil BL, CH;
Martin Graf, Zeiningen, CH;
Roberto Iacone, Basel, CH;
Ravi Jagasia, Loerrach, DE;
Assignee:
HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 5/0797 (2010.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 5/0623 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/119 (2013.01); C12N 2501/13 (2013.01); C12N 2501/405 (2013.01); C12N 2501/60 (2013.01); C12N 2501/602 (2013.01); C12N 2501/727 (2013.01); C12N 2506/1307 (2013.01); C12N 2510/00 (2013.01);
Abstract
This application relates to a method for converting somatic cells to Neural Stem Cells (NSCs). Moreover this application relates to a method for converting human fibroblasts, keratinocytes or adipocytes to neural stem cells based on linked steps of genes transduction and chemically defined medium induction.