The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2016
Filed:
Jun. 11, 2013
Promis Neurosciences Inc., Toronto, CA;
Helix Biopharma Corp., Aurora, CA;
Marni Diane Uger, Richmond Hill, CA;
Viengthong Chai, Brampton, CA;
Veronica Ciolfi, Brampton, CA;
Neil R. Cashman, Vancouver, CA;
Baomin Tian, Edmonton, CA;
Wah Yau Wong, Edmonton, CA;
Heman Lap-Man Chao, Aurora, CA;
ProMIS Neurosciences Inc., Toronto, ON, CA;
Helix BioPharma Corp., Aurora, ON, CA;
Abstract
Human prion protein, PrP, selectively presents the epitope MDEYSNQNN (SEQ ID No. 14) when PrP misfolds. The misfolded form of human PrP is associated with various disease states. The present invention provides an antibody useful to detect and treat such diseases, including cancer such as ovarian cancer and lymphomas, and transmissible spongiform encephalopathies such as CJD. Also provided is an immunoconjugate in which the antibody is conjugated with urease as cytotoxin.