The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2016

Filed:

May. 23, 2013
Applicant:

Cellzome Limited, Brentford, Middlesex, GB;

Inventors:

Richard John Harrison, Cambridgeshire, GB;

Nigel Ramsden, Hertfordshire, GB;

Jeremy Major, Brentford, GB;

Adeline Morel, Essex, GB;

Laura Convery, Hertfordshire, GB;

Mihiro Sunose, Cambridgeshire, GB;

Rosemary Lynch, Cambridgeshire, GB;

Rita Adrego, Suffolk, GB;

Alison Jones, Cambridgeshire, GB;

Assignee:

Cellzome Limited, Brentford, Middlesex, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); C07D 403/14 (2006.01); C07D 407/14 (2006.01); C07D 417/14 (2006.01); C07D 471/08 (2006.01); C07D 487/10 (2006.01); C07D 491/048 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 407/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/08 (2013.01); C07D 487/10 (2013.01); C07D 491/048 (2013.01); C07D 491/107 (2013.01);
Abstract

The present invention relates to compounds of formula (I) wherein R, R, Xto Xhave the meaning as cited in the description and the claims. Said compounds are useful as TYK2 inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds as well as their use as medicaments.


Find Patent Forward Citations

Loading…