The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2016
Filed:
Mar. 07, 2008
Hanne Everland, Bagsvaerd, DK;
Jacob Vange, Helsingoer, DK;
Christian Clausen, Fredensborg, DK;
Lene Feldskov Nielsen, Copenhagen K, DK;
Hanne Everland, Bagsvaerd, DK;
Jacob Vange, Helsingoer, DK;
Christian Clausen, Fredensborg, DK;
Lene Feldskov Nielsen, Copenhagen K, DK;
Coloplast A/S, Humlebaek, DK;
Abstract
The present application discloses that incorporation of dermatan sulfate and/or HA in composite scaffolds of certain polymers gives rise to a chondrogenic effect on chondrocytes resulting in formation of cartilage that resembles the natural ECM. This effect with dermatan sulfate as the primary additive has not previously been seen. The composites are formed by incorporation of dermatan sulfate finely dispersed particles optionally nanoparticles or as molecular dissolutions in a polymer matrix with no bonding between the DS and the matrix, providing the DS to the chondrocytes in an accessible non-crosslinked form.