The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2016

Filed:

Aug. 10, 2012
Applicants:

Roger Schibli, Baden, CH;

Rudolf Moser, Schaffhausen, CH;

Cristina Magdalena Muller, Nussbaumen, CH;

Harriet Struthers, Basel, CH;

Viola Groehn, Dachsen, CH;

Simon Mensah Ametamey, Zurich, CH;

Cindy Ramona Fischer, Zurich, CH;

Inventors:

Roger Schibli, Baden, CH;

Rudolf Moser, Schaffhausen, CH;

Cristina Magdalena Muller, Nussbaumen, CH;

Harriet Struthers, Basel, CH;

Viola Groehn, Dachsen, CH;

Simon Mensah Ametamey, Zurich, CH;

Cindy Ramona Fischer, Zurich, CH;

Assignee:

MERCK & CIE, Schaffhausen, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61K 49/00 (2006.01); A61K 51/04 (2006.01); A61K 47/48 (2006.01); C07D 475/04 (2006.01); G01N 33/569 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0497 (2013.01); A61K 47/48107 (2013.01); A61K 51/0472 (2013.01); A61K 51/0491 (2013.01); C07D 475/04 (2013.01); G01N 33/56966 (2013.01); C07B 59/002 (2013.01);
Abstract

The present invention is directed towards new trifunctional folate-conjugates comprising a folate, an albumin binder and a radionuclide-based therapeutic or diagnostic moiety as well as pharmaceutical compositions thereof, their method of production and their use in diagnostic and therapeutic medical applications, such as diagnostic nuclear imaging and radionuclide therapy.


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