logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9295722 B1

PDFFull Text
Expired
Date of Patent:
Mar. 29, 2016

Filed:

Jan. 26, 2006

Bacterial glycolipid activation of cd1d-restricted nkt cells

Applicants:

Paul B. Savage, Mapleton, UT (US);

Albert Bendelac, Chicago, IL (US);

Luc Teyton, Del Mar, CA (US);

Inventors:

Paul B. Savage, Mapleton, UT (US);

Albert Bendelac, Chicago, IL (US);

Luc Teyton, Del Mar, CA (US);

Assignees:

THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);

THE UNIVERSITY OF CHICAGO, Chicago, IL (US);

BRIGHAM YOUNG UNIVERSITY, Provo, UT (US);

Attorney:

Merchant & Gould P.C.

Primary Examiner:

Gary Nickol

Assistant Examiner:

Mary Lyons

Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07H 17/02 (2006.01); A61K 31/70 (2006.01); A61K 31/74 (2006.01); A61K 39/39 (2006.01); A61K 31/7032 (2006.01); A61K 35/74 (2015.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 31/7032 (2013.01); A61K 35/74 (2013.01); A61K 38/1774 (2013.01); A61K 2039/55594 (2013.01);
Abstract

Disclosed are methods for activating an NKT cell, methods of stimulating an immune response in a subject, methods of improving vaccine efficacy, and methods of treating an infection. Also disclosed are methods of promoting tumor rejection, treating cancer, modulating autoimmunity and inhibiting allergen-induced hypersensitivity in subjects. The methods include contacting an NKT cell with a bacterial glycolipid complexed with a CD1 molecule to activate the NKT cell. The bacterial glycolipid may be derived from a member of the Class Alphaproteobacteria.

Find Patent Forward Citations

Savage, Paul. (2016). Bacterial glycolipid activation of cd1d-restricted nkt cells (U.S. Patent No. 9295722). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9295722

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…