The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2016

Filed:

Mar. 16, 2012
Applicants:

Alan Berezov, West Hollywood, CA (US);

Mark I. Greene, Penn Valley, PA (US);

Natalie Minkovsky, Philadephia, PA (US);

Zheng Cai, Wynnewood, PA (US);

Hongtao Zhang, Paoli, PA (US);

Inventors:

Alan Berezov, West Hollywood, CA (US);

Mark I. Greene, Penn Valley, PA (US);

Natalie Minkovsky, Philadephia, PA (US);

Zheng Cai, Wynnewood, PA (US);

Hongtao Zhang, Paoli, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/573 (2006.01); A61K 31/4525 (2006.01); A61K 31/44 (2006.01); A61K 31/505 (2006.01); A61K 31/4184 (2006.01); A61K 31/4418 (2006.01); A61K 31/517 (2006.01); A61K 31/635 (2006.01); A61K 45/06 (2006.01); A61K 31/57 (2006.01); C07D 213/76 (2006.01); C07D 239/42 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07J 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/573 (2013.01); A61K 31/4184 (2013.01); A61K 31/44 (2013.01); A61K 31/4418 (2013.01); A61K 31/4525 (2013.01); A61K 31/505 (2013.01); A61K 31/517 (2013.01); A61K 31/57 (2013.01); A61K 31/635 (2013.01); A61K 45/06 (2013.01); C07D 213/76 (2013.01); C07D 239/42 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07J 7/008 (2013.01);
Abstract

This invention is in the fields of cancer therapy. More particularly it concerns compounds which are useful agents for treating cell proliferative disorders, especially those disorders characterized by over activity and/or inappropriate activity of a EGFR, including EGFR-related cancers, particularly for expanding the efficacy of drugs previously developed for this purpose, and for methods of treatments using the compounds for this purpose.


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