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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9295673 B1

PDFFull Text
Date of Patent:
Mar. 29, 2016

Filed:

Feb. 23, 2012

Combination of mtor inhibitors and p13-kinase inhibitors, and uses thereof

Applicants:

Pingda Ren, San Diego, CA (US);

Yi Liu, San Diego, CA (US);

Katayoun Jessen, San Diego, CA (US);

Xin Guo, San Diego, CA (US);

Christian Rommel, La Jolla, CA (US);

Troy Edward Wilson, San Marino, CA (US);

Inventors:

Pingda Ren, San Diego, CA (US);

Yi Liu, San Diego, CA (US);

Katayoun Jessen, San Diego, CA (US);

Xin Guo, San Diego, CA (US);

Christian Rommel, La Jolla, CA (US);

Troy Edward Wilson, San Marino, CA (US);

Assignee:

Intellikine LLC, La Jolla, CA (US);

Attorneys:

Honigman Miller Schwartz and Cohn LLP

Lucy X. Yang

Jonathan P. O'Brien

Primary Examiner:

Anna Pagonakis

Int. Cl.
CPC ...
A61K 31/551 (2006.01); A61K 31/4439 (2006.01); A61K 31/4745 (2006.01); A61K 31/498 (2006.01); A61K 45/06 (2006.01); A61K 31/501 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/527 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01);
U.S. Cl.
CPC ...
A61K 31/551 (2013.01); A61K 31/4439 (2013.01); A61K 31/4745 (2013.01); A61K 31/498 (2013.01); A61K 31/501 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/527 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth.

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