The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
May. 06, 2014
Applicant:
Gradalis, Inc., Carrollton, TX (US);
Inventor:
Donald Rao, Dallas, TX (US);
Assignee:
STRIKE BIO, Inc., Dallas, TX (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 48/00 (2006.01); C12N 15/85 (2006.01); C12N 15/11 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 48/00 (2013.01); C12N 15/111 (2013.01); C12N 15/85 (2013.01); A61K 9/0019 (2013.01); C12N 2310/51 (2013.01); C12N 2330/51 (2013.01);
Abstract
A method for designing a bi-shRNA expression cassette encoding a bi-shRNA comprising: selecting one or more target site sequences; providing a backbone sequence comprising a first and a second stem-loop structure, inserting a first passenger strand and a second passenger strand and providing for synthesis of the bi-shRNA expression cassette.