The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Nov. 04, 2010
M. Edward Medof, Pepper Pike, OH (US);
Feng Lin, Willoughby, OH (US);
Michael G. Strainic, Westlake, OH (US);
M. Edward Medof, Pepper Pike, OH (US);
Feng Lin, Willoughby, OH (US);
Michael G. Strainic, Westlake, OH (US);
Case Western Reserve University, Cleveland, OH (US);
Abstract
A method of generating a CD4FoxP3Treg cell, the method includes administering at least one complement antagonist to a naive CD4T cell at an amount effective to substantially inhibits C3a receptor (C3aR) and/or C5a receptor (C5aR) signal transduction in the CD4T cell, induce TGF-β1 expression of the CD4T cell, and induce differentiation of the of the naive CD4T cell into a CD4FoxP3Treg cell.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile