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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9290582 B1

PDFFull Text
Date of Patent:
Mar. 22, 2016

Filed:

May. 26, 2011

B cell activating factor antagonist and preparation method and use thereof

Applicants:

LI Yang, Chengdu, CN;

Yuquan Wei, Chengdu, CN;

Inventors:

Li Yang, Chengdu, CN;

Yuquan Wei, Chengdu, CN;

Assignees:

CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD., Shijiazhuang, CN;

SICHUAN UNIVERSITY, Chengdu, CN;

Attorney:

Caesar Rivise, PC

Primary Examiner:

Robert Landsman

Assistant Examiner:

Bruce D Hissong

Int. Cl.
CPC ...
C07K 19/00 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61K 31/7088 (2006.01);
U.S. Cl.
CPC ...
C07K 19/00 (2013.01); A61K 31/7088 (2013.01); C07K 14/4703 (2013.01); C07K 14/70578 (2013.01); A61K 38/00 (2013.01); A61K 48/005 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to the field of genetic engineering drugs, particularly to a novel B cell activating factor (BAFF) antagonist and use thereof. The technical problem to be solved by the invention is to find a new and effective selection for the prevention and treatment of autoimmune diseases. The B cell activating factor receptor antagonist is mainly obtained by the fusion of the domain 2 binding BAFF in TACI receptor and the domain binding BAFF in Br3 receptor, and it also can be fused with a Fc segment of IgG1 to obtain a new fusion protein molecule. Experiments indicate that said new fusion protein molecule has the function of BAFF antagonist, which can treat the autoimmune diseases, and supply a new and effective selection for the prevention and treatment of the autoimmune diseases.

Find Patent Forward Citations

Yang, Li. (2016). B cell activating factor antagonist and preparation method and use thereof (U.S. Patent No. 9290582). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9290582

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