The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2016

Filed:

Jul. 02, 2010
Applicants:

Peter J. Hudson, Blackburn, AU;

Paul R. Sanders, Moonee Ponds, AU;

Debra Tamvakis, Camberwell, AU;

Fabio Turatti, Docklands, AU;

Michael P. Wheatcroft, Southbank, AU;

David Leong, Preston, AU;

Inventors:

Peter J. Hudson, Blackburn, AU;

Paul R. Sanders, Moonee Ponds, AU;

Debra Tamvakis, Camberwell, AU;

Fabio Turatti, Docklands, AU;

Michael P. Wheatcroft, Southbank, AU;

David Leong, Preston, AU;

Assignee:

AVIPEP PTY LIMITED, Parkville, Victoria, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/10 (2006.01); C07K 16/30 (2006.01); A61K 47/48 (2006.01); C07K 16/32 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 47/48676 (2013.01); A61K 51/10 (2013.01); A61K 51/1093 (2013.01); C07K 16/3092 (2013.01); C07K 16/32 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/622 (2013.01); C07K 2317/624 (2013.01); C07K 2317/626 (2013.01); C07K 2319/31 (2013.01);
Abstract

The present invention provides an isolated protein comprising an immunoglobulin variable region comprising at least two cysteine residues positioned within framework region 1 such that if at least two of the cysteine residues are not conjugated to another compound a disulphide bond forms between the cysteine residues. Preferably the protein comprises an immunoglobulin heavy chain variable region and an immunoglobulin light chain variable region, wherein at least one of the variable regions comprises the two cysteine residues. The present invention also provides a protein that binds to TAG72. The present invention also provides conjugates of the protein and another compound.


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Hudson, Peter. (2016). Immuno-conjugates and methods for producing them (U.S. Patent No. 9290577). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9290577

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