The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Feb. 18, 2011
Applicants:
Stephen Nishimura, Mill Valley, CA (US);
Jianlong Lou, San Bruno, CA (US);
Jody Lynn Baron, Mill Valley, CA (US);
James D. Marks, Kensington, CA (US);
Inventors:
Stephen Nishimura, Mill Valley, CA (US);
Jianlong Lou, San Bruno, CA (US);
Jody Lynn Baron, Mill Valley, CA (US);
James D. Marks, Kensington, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 14/705 (2006.01); C07H 21/00 (2006.01); C12P 21/06 (2006.01); C12P 19/34 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2839 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present invention relates to αvβ8 antagonists, anti-αvβ8 antibodies or immunoconjugates for reducing TGFβ activation in an individual. Further provided are compositions comprising one of the αvβ8 antagonists, anti-αvβ8 antibodies or immunoconjugates, methods for using the compositions, and related subject matter.