The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Jun. 06, 2013
Applicant:
Hoffmann-la Roche Inc., Nutley, NJ (US);
Inventors:
Bernd Bohrmann, Riehen, CH;
Ulrich Goepfert, Penzberg, DE;
Fiona Grueninger, Arlesheim, CH;
Walter Huber, Kaiseraugst, CH;
Hans-Willi Krell, Penzberg, DE;
Valeria Lifke, Penzberg, DE;
Olaf Mundigl, Weilheim, DE;
Sonja Offner, Penzberg, DE;
Laurence Ozmen, Saint Louis, FR;
Michael Schraemi, Penzberg, DE;
Assignee:
Hoffmann-La Roche Inc., Nutley, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 14/47 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); C07K 14/4711 (2013.01); C07K 16/3053 (2013.01); A61K 2039/505 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/40 (2013.01); C07K 2319/55 (2013.01);
Abstract
An antibody binding to Tau that is phosphorylated at serine 422 (pS422), which specifically binds to phosphorylated Tau fragment of SEQ ID NO:9 and to Tau pS422, but does not bind to Tau and to phosphorylated MCAK fragment of SEQ ID NO:17. The antibody is useful in the treatment of a Tauopathy.