The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2016

Filed:

Mar. 15, 2012
Applicants:

Jong-seung Kim, Gyeonggi-do, KR;

Sankarprasad Bhuniya, Seoul, KR;

Sumin Lee, Seoul, KR;

Kwan Soo Hong, Chungcheongbuk-do, KR;

Hyunseung Lee, Chungcheongbuk-do, KR;

Hyeyoung Moon, Chungcheongbuk-do, KR;

Inventors:

Jong-Seung Kim, Gyeonggi-do, KR;

Sankarprasad Bhuniya, Seoul, KR;

Sumin Lee, Seoul, KR;

Kwan Soo Hong, Chungcheongbuk-do, KR;

Hyunseung Lee, Chungcheongbuk-do, KR;

Hyeyoung Moon, Chungcheongbuk-do, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F 5/00 (2006.01); C07H 23/00 (2006.01); A61K 49/10 (2006.01); C07H 19/067 (2006.01);
U.S. Cl.
CPC ...
C07H 23/00 (2013.01); A61K 49/103 (2013.01); C07F 5/003 (2013.01); C07H 19/067 (2013.01);
Abstract

The present invention relates to a new uridine nucleoside-based amphiphilic gadolinium complex and a magnetic resonance imaging (MRI) contrast agent including the gadolinium complex. The MRI contrast agent has high relaxivity, high binding affinity for and stability in human serum albumin, pH response, and high liver specificity.


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