The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Dec. 19, 2014
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
Craig J. Thomas, Gaithersburg, MD (US);
Douglas S. Auld, Beverly, MA (US);
James Inglese, Bethesda, MD (US);
Amanda P. Skoumbourdis, Langhorne, PA (US);
Jian-Kang Jiang, Columbia, MD (US);
Matthew B. Boxer, New Market, MD (US);
Abstract
Disclosed are pyruvate kinase M2 activators, which are, bis sulfonamide piperazinyl compounds of Formula (I) and 2,4-disubstituted 4H-thieno[3,2-b]pyrrole-2-(substituted benzyl)pyridazin-3(2H)ones of Formula (II), wherein L and Rto Rare as defined herein, that are useful in treating a number of diseases that are treatable by the activation of PKM2, for example, cancer and anemia, Formulas (I); (II).