The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2016

Filed:

Nov. 15, 2012
Applicant:

Xention Limited, Cambridge, GB;

Inventors:

David Madge, Cambridge, GB;

Fiona Chan, Cambridge, GB;

Derek Edward John, Cambridge, GB;

Simon D. Edwards, Cambridge, GB;

Richard Blunt, Cambridge, GB;

Basil Hartzoulakis, Cambridge, GB;

Lindsay Brown, Cambridge, GB;

Assignee:

Xention Limited, Cambridge, GB;

Attorney:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/519 (2006.01); A61P 9/06 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 31/519 (2013.01); C07D 491/048 (2013.01);
Abstract

The present invention provides compounds of formula (I): (Formula (I); wherein A, R, R, R, V, X, and Z are defined herein, which are potassium channel inhibitors. The invention further provides pharmaceutical compositions comprising the compounds of formula (I) and their use in therapy, in particular in treatment of diseases or conditions that are mediated by K3.1 and/or K3.4 or any heteromultimers thereof, or that require inhibition of K3.1 and/or K3.4 or any heteromultimers thereof.


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