The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
May. 04, 2012
Michael D. Altman, Needham, MA (US);
Kaleen Konrad Childers, Newton, MA (US);
Maria Emilia Di Francesco, Houston, TX (US);
John Michael Ellis, Needham, MA (US);
Christian Fischer, Natick, MA (US);
Jonathan Grimm, Ashburn, VA (US);
Andrew M. Haidle, Cambridge, MA (US);
Solomon D. Kattar, Arlington, MA (US);
Alan B. Northrup, Reading, MA (US);
Ryan D. Otte, Natick, MA (US);
Alessia Petrocchi, Houston, TX (US);
Adam J. Schell, Decatur, GA (US);
Hua Zhou, Acton, MA (US);
Michael D. Altman, Needham, MA (US);
Kaleen Konrad Childers, Newton, MA (US);
Maria Emilia Di Francesco, Houston, TX (US);
John Michael Ellis, Needham, MA (US);
Christian Fischer, Natick, MA (US);
Jonathan Grimm, Ashburn, VA (US);
Andrew M. Haidle, Cambridge, MA (US);
Solomon D. Kattar, Arlington, MA (US);
Alan B. Northrup, Reading, MA (US);
Ryan D. Otte, Natick, MA (US);
Alessia Petrocchi, Houston, TX (US);
Adam J. Schell, Decatur, GA (US);
Hua Zhou, Acton, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis and cancer.