The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Jul. 05, 2013
Applicant:
Duke University, Durham, NC (US);
Inventors:
Wolfgang Liedtke, Durham, NC (US);
Farshid Guilak, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/04 (2006.01); A61K 31/4439 (2006.01); A01K 67/027 (2006.01); C07K 14/705 (2006.01); C07D 277/42 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); A01K 67/0275 (2013.01); A01K 67/0276 (2013.01); A61K 31/4439 (2013.01); C07D 277/42 (2013.01); C07K 14/705 (2013.01); G01N 33/6881 (2013.01); A01K 2217/075 (2013.01); A01K 2217/206 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01);
Abstract
Provided are TRPV4 inhibitor compounds. Further provided are compositions including a TRPV4 inhibitor compound in combination with a carrier, vehicle, or diluent that is suitable for topical application. The TRPV4 inhibitor compounds and compositions may be used in methods of treating and/or preventing dermatological disorders, reducing skin inflammation, reducing pain, and/or reducing itch in a subject in need thereof.