The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Jan. 16, 2013
Shanghai Kechow Pharma, Inc., Shanghai, CN;
Hongqi Tian, Tianjin, CN;
Conghui Ji, Tianjin, CN;
Chunlei Liu, Tianjin, CN;
Li Kong, Tianjin, CN;
Ying Cheng, Tianjin, CN;
Gongchao Huang, Tianjin, CN;
SHANGHAI KECHOW PHARMA, INC., Shanghai, CN;
Abstract
Disclosed are compound of formula (I) and pharmaceutically accepted salts and prodrugs thereof, wherein each of R, R, R, R, R, R, Xand Xis as defined in the description. These compounds are protein kinases inhibitors, especially the inhibitors of Mek, which are useful in the treatment of cancers and inflammation of mammals. Disclosed are the treatment methods of cancers and inflammation of mammals as well as pharmaceutical compositions comprising the compounds described herein. The preparation of benzoheterocyclic compounds are disclosed. Disclosed are the preparation of potential drug candidates, such as benzooxazol, benzothiazol, benzothiadiazol and the like.