The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2016

Filed:

Nov. 09, 2015
Applicant:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Inventors:

Christian Gnamm, Biberach an der Riss, DE;

Thorsten Oost, Biberach an der Riss, DE;

Stefan Peters, Biberach an der Riss, DE;

Holger Hoesch, Biberach an der Riss, DE;

Uwe Joerg Ries, Biberach an der Riss, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Int. Cl.
CPC ...
C07D 239/70 (2006.01); C07D 403/12 (2006.01); C07D 401/12 (2006.01); A61K 31/517 (2006.01); A61P 9/12 (2006.01);
U.S. Cl.
CPC ...
C07D 239/70 (2013.01); A61K 31/517 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01);
Abstract

This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.


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