The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2016

Filed:

Aug. 07, 2014
Applicants:

Battelle Memorial Institute, Richland, WA (US);

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Darrell R. Fisher, Richland, WA (US);

You Han Bae, Salt Lake City, UT (US);

Zhonggao Gao, Salt Lake City, UT (US);

Assignees:

Battelle Memorial Institute, Richland, WA (US);

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61N 5/10 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 51/06 (2006.01); A61K 51/12 (2006.01); A61B 19/00 (2006.01);
U.S. Cl.
CPC ...
A61N 5/1001 (2013.01); A61B 19/54 (2013.01); A61K 9/0024 (2013.01); A61K 9/1647 (2013.01); A61K 51/06 (2013.01); A61K 51/1251 (2013.01); A61B 2019/5466 (2013.01); A61N 2005/1024 (2013.01); A61N 2005/1087 (2013.01); A61N 2005/1089 (2013.01);
Abstract

A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta- or alpha-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved so as to release the microspheres from the polymer matrix. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding or minimizing undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method.


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