The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2016

Filed:

Aug. 21, 2009
Applicants:

Natalia V. Lisitza, Brookline, MA (US);

Eduard Y. Chekmenev, Nashville, TN (US);

Samuel Patz, Chestnut Hill, MA (US);

Inventors:

Natalia V. Lisitza, Brookline, MA (US);

Eduard Y. Chekmenev, Nashville, TN (US);

Samuel Patz, Chestnut Hill, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/10 (2006.01); G01R 33/28 (2006.01);
U.S. Cl.
CPC ...
A61K 49/10 (2013.01); G01R 33/282 (2013.01);
Abstract

A method of preparing a hydrogen-containingC compound test sample exhibiting an enhancedC nuclear magnetic resonance (NMR) signal when exposed to aC NMR pulse sequence is disclosed. In the disclosed method, the hydrogen-containingC compound is mixed with hyperpolarizedXe in the gaseous state, and the mixture is subsequently frozen within a magnetic field. The magnetic field strength is then reduced sufficiently so that spin polarization is transferred from the hyperpolarizedXe to the compound. The magnetic field strength is then increased, and the mixture is thawed to obtain the test sample.


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