The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Nov. 25, 2013
Applicant:
The Boeing Company, Chicago, IL (US);
Inventor:
Maurice P. Bianchi, Palos Verdes Estate, CA (US);
Assignee:
The Boeing Company, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61N 5/06 (2006.01); B82Y 5/00 (2011.01); A61K 33/06 (2006.01); A61K 33/22 (2006.01); A61K 33/24 (2006.01); A61K 33/30 (2006.01); A61K 33/44 (2006.01); A61K 41/00 (2006.01); C07K 16/28 (2006.01); A61B 18/18 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48376 (2013.01); A61B 18/18 (2013.01); A61K 33/06 (2013.01); A61K 33/22 (2013.01); A61K 33/24 (2013.01); A61K 33/30 (2013.01); A61K 33/44 (2013.01); A61K 41/0042 (2013.01); A61K 47/48092 (2013.01); A61K 47/48623 (2013.01); A61K 47/48723 (2013.01); A61N 5/0624 (2013.01); B82Y 5/00 (2013.01); C07K 16/2833 (2013.01); A61N 5/10 (2013.01); A61N 2005/1085 (2013.01); Y10S 977/774 (2013.01); Y10S 977/904 (2013.01); Y10S 977/911 (2013.01);
Abstract
The present disclosure relates to compositions and methods for the treatment of a disease, e.g., cancer or pathogenic infection, using a bioconjugated nanoparticle comprising a biocompatible quantum dot conjugated to a targeting moiety. The targeting moiety allows for the nanopaticle to bind to a cancer cell or pathogenic organism. The quantum dot, upon excitation by soft x-rays, emits electromagnetic radiation at a frequency of ultraviolet light, thereby allowing for the disruption of the DNA found in the cancer cell or pathogenic organism.