The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Mar. 07, 2011
Huaizhong Pan, Salt Lake City, UT (US);
Jiyuan Yang, Salt Lake City, UT (US);
Pavla Kopeckova, Salt Lake City, UT (US);
Kui Luo, Salt Lake City, UT (US);
Jindrich Kopecek, Salt Lake City, UT (US);
Huaizhong Pan, Salt Lake City, UT (US);
Jiyuan Yang, Salt Lake City, UT (US);
Pavla Kopeckova, Salt Lake City, UT (US);
Kui Luo, Salt Lake City, UT (US);
Jindrich Kopecek, Salt Lake City, UT (US);
University of Utah Research Foundation, Salt Lake City, UT (US);
Abstract
Described herein are biodegradable drug delivery conjugates for effectively delivering bioactive agents to a subject. The drug delivery conjugates comprise a water-soluble high molecular weight linear biodegradable polymer backbone comprising a plurality of linear water-soluble polymeric segments connected to one another by a first (main-chain) cleavable linker, wherein a bioactive agent is covalently bonded to at least one water-soluble polymeric segment, at least one cleavable linker, or a combination thereof. The conjugates possess numerous advantages over prior art delivery conjugates. Also described herein are methods for making and using the conjugates.