The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2016

Filed:

Jul. 02, 2012
Applicants:

Sebastiaan Antonius Martinus Waltherus Van Den Broek, Nijmegen, NL;

Pieter Jos Nieuwland, Nijmegen, NL;

Kaspar Koch, Nijmegen, NL;

Inventors:
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2006.01); A61K 9/51 (2006.01); B82Y 5/00 (2011.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 9/146 (2013.01); A61K 9/5169 (2013.01); A61K 9/5192 (2013.01); B82Y 5/00 (2013.01);
Abstract

A continuous process for the preparation of gelatin based nanoparticles in a reactor having a process channel having a mixing element therein, the process having the following steps: A) feeding separately an aqueous gelatin solution at a first rate and a water-miscible organic solvent at a second rate to the process channel of the reactor to be mixed therein, to form a suspension of non-crosslinked gelatin based nanoparticles and B) crosslinking the non-crosslinked gelatin based nanoparticles, wherein the sum of the first rate and the second rate is chosen such that the reactor has a mixing efficiency as determined by the Villermaux/Dushman method of between 0.1 and 1.5 and the period from the time point at which the aqueous gelatin solution is fed to the reactor to the time point at which the mixture of the aqueous gelatin solution and the organic solvent contacts the mixing element is at most 15 seconds.


Find Patent Forward Citations

Van Den Broek, Sebastiaan Antonius Martinus Waltherus. (2016). Continuous flow production of gelatin nanoparticles (U.S. Patent No. 9289499). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9289499

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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