The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Aug. 12, 2011
Applicants:
David Hickman, Saint-Sulpice, CH;
Maria Pilar Lopez-deber, Lausanne, CH;
Andreas Muhs, Cugy, CH;
Inventors:
Assignee:
AC Immune SA, Lausanne, CH;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
A61K 39/385 (2013.01); A61K 39/0007 (2013.01); C07K 16/18 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/6018 (2013.01); A61K 2039/64 (2013.01); G01N 2405/00 (2013.01); G01N 2440/10 (2013.01);
Abstract
The method and constructs disclosed and claimed herein allow to control peptide conformation by modulation of the peptide lipidation pattern, spacer and liposome composition, or via co-administration with small molecules. Accordingly, this technology can be applied to the rational design of liposomal vaccines and for the generation of safer and more efficacious therapies for a range of human disease, in particular those based on misfolded proteins.