The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2016
Filed:
Feb. 06, 2015
Applicant:
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Inventor:
Kai Suzuki, Osaka, JP;
Assignee:
OTSUKA PHARMACEUTICAL CO., LTD., Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 31/55 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1635 (2013.01); A61K 9/1623 (2013.01); A61K 9/20 (2013.01); A61K 31/55 (2013.01); A61K 9/2072 (2013.01); A61K 9/2095 (2013.01);
Abstract
The present invention aims to provide a matrix-type solid preparation that has high-level release controllability for suppressing drug release in the upper gastrointestinal tract and accelerating drug release in the lower gastrointestinal tract, and that solves of all the above drawbacks caused by combining a plasticizer. The present invention provides a method for producing a matrix-type pharmaceutical solid preparation that contains: (a) a methacrylic acid-based enteric polymer; (b) a sugar and/or a sugar alcohol, and (c) tolvaptan.