The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Nov. 14, 2012
Applicants:

Abbott Molecular Inc., Des Plaines, IL (US);

National Institute of Health, Rockville, MD (US);

Inventors:

Olli-P Kallioniemi, Rockville, MD (US);

Uwe Richard Muller, Painted Post, NY (US);

Guido Sauter, Basel, CH;

Juha Kononen, Rockville, MD (US);

Maarit Barlund, Tampere, FI;

Assignee:

Abbott Molecular Inc., Des Plaines, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12Q 1/68 (2006.01); B01L 3/00 (2006.01); G01N 1/28 (2006.01); G01N 1/31 (2006.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); G02B 21/34 (2006.01); G01N 1/08 (2006.01); G01N 1/36 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); B01L 3/5085 (2013.01); C12Q 1/6809 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6841 (2013.01); G01N 1/2813 (2013.01); G01N 1/312 (2013.01); G01N 33/5005 (2013.01); G01N 33/54306 (2013.01); G02B 21/34 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/00702 (2013.01); B01J 2219/00743 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); G01N 1/08 (2013.01); G01N 2001/282 (2013.01); G01N 2001/288 (2013.01); G01N 2001/368 (2013.01);
Abstract

A method is disclosed for rapid molecular profiling of tissue or other cellular specimens by placing a donor specimen in an assigned location in a recipient array, providing copies of the array, and performing a different biological analysis of each copy. The results of the different biological analyses are compared to determine if there are correlations between the results of the different biological analyses at each assigned location. In some embodiments, the specimens may be tissue specimens from different tumors, which are subjected to multiple parallel molecular (including genetic and immunological) analyses. The results of the parallel analyses are then used to detect common molecular characteristic of the genetic disorder type, which can subsequently be used in the diagnosis or treatment of the disease. The biological characteristics of the tissue can be correlated with clinical or other information, to detect characteristics associated with the tissue.


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