The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Jun. 06, 2014
Applicant:
Bayer Pharmaceuticals Corporation, Berkeley, CA (US);
Inventors:
Sham-Yuen Chan, El Sobrante, CA (US);
Hsinyi Yvette Tang, Piedmont, CA (US);
Yiwen Tao, San Diego, CA (US);
Yongjian Wu, San Diego, CA (US);
Ruth Kelly, Athens, OH (US);
Assignee:
BAYER HEALTHCARE LLC, Whippany, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C07K 14/755 (2006.01); C12N 5/00 (2006.01); C07K 14/81 (2006.01); C12N 15/85 (2006.01); C12P 21/00 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C07K 14/435 (2013.01); C07K 14/755 (2013.01); C07K 14/8114 (2013.01); C12N 5/00 (2013.01); C12N 15/85 (2013.01); C12P 21/00 (2013.01); C12N 2501/07 (2013.01); C12N 2501/998 (2013.01); C12N 2510/02 (2013.01);
Abstract
The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein.