The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Apr. 02, 2013
Applicants:
Katie Jansen Spayd, Huntsville, AL (US);
Jon Karpilow, Boulder, CO (US);
John K. Wakefield, Birmingham, AL (US);
Inventors:
Katie Jansen Spayd, Huntsville, AL (US);
Jon Karpilow, Boulder, CO (US);
John K. Wakefield, Birmingham, AL (US);
Assignee:
GE Healthcare Dharmacon, Inc., Lafayette, CO (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/01 (2006.01); C12N 7/02 (2006.01); C12N 15/86 (2006.01); A61K 39/21 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/86 (2013.01); C12N 2740/15051 (2013.01); C12N 2740/15052 (2013.01);
Abstract
The present disclosure provides a method of modifying cells in order to enhance lentiviral titers, cell lines that are modified and modifying reagents. By mediating individual genes and combination thereof, lentiviral titers may be increased.