The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Jun. 18, 2010
Applicants:
Harald Stachelscheid, Berlin, DE;
Katrin Zeilinger, Berlin, DE;
Janne Jensen, Gothenburg, SE;
Thomas Urbaniak, Berlin, DE;
Inventors:
Harald Stachelscheid, Berlin, DE;
Katrin Zeilinger, Berlin, DE;
Janne Jensen, Gothenburg, SE;
Thomas Urbaniak, Berlin, DE;
Assignee:
Takara Bio Europe AB, Goteborg, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 5/071 (2010.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12N 5/067 (2013.01); C12M 25/10 (2013.01); C12N 5/0671 (2013.01); C12N 2500/25 (2013.01); C12N 2500/34 (2013.01); C12N 2501/11 (2013.01); C12N 2501/113 (2013.01); C12N 2501/115 (2013.01); C12N 2501/12 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/23 (2013.01); C12N 2501/39 (2013.01); C12N 2501/70 (2013.01); C12N 2506/02 (2013.01);
Abstract
The present invention relates to the use of 3D culturing systems for the derivation of hepatocyte-like cells from human pluripotent stem cells (hPS). In particular, the invention concerns the directed differentiation and maturation of human pluripotent stem cells into hepatocyte like cells in 3D hollow fiber capillary bioreactors.