The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Nov. 20, 2013
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Huiquan Han, Thousand Oaks, CA (US);
Keith Soo-Nyung Kwak, Thousand Oaks, CA (US);
Xiaolan Zhou, Newbury Park, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 5/02 (2006.01); C12N 15/00 (2006.01); C07K 14/71 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention provides novel activin IIB5 receptor polypeptides capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the receptor polypeptides. Compositions and methods for treating muscle-wasting, metabolic and other disorders are also provided.