The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Nov. 04, 2010
Applicants:

Timothy David Gross, San Diego, CA (US);

Rathan Prasad Achampeta, Secunderabad-A.P, IN;

Janakiram Rao Citineni, Florence, SC (US);

Inventors:

Timothy David Gross, San Diego, CA (US);

Rathan Prasad Achampeta, Secunderabad-A.P, IN;

Janakiram Rao Citineni, Florence, SC (US);

Assignee:

Ambit Biosciences Corporation, San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 265/30 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01);
Abstract

Provided herein are process for the preparation of N-(5-ferf-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-fe][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt, solvate, hydrate, or polymorph thereof. N-(5-tert-Butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-&][1,3]benzo-thiazol-2-yl]phenyl}urea is useful for treating, preventing, and/or managing diseases or conditions, including but not limited to, proliferative diseases, FLT-3 mediated diseases, and cancers. N-(5-ferf-Butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-&][1,3]benzothiazol-2-yl]phenyl}urea is represented by the structure:


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